Effekt osnovannyh na metaplastichnosti protokolov transkranial'noj stimulyacii teta-vspyshkami na pokazateli rabochej pamyati
نویسندگان
چکیده
Issledovanie protokolov transkranial'noj magnitnoj stimulyacii (TMS), osnovannyh na metaplastichnosti, yavlyaetsya intensivno izuchaemym podhodom k uluchsheniyu effektivnosti stimulyacii. Odnako effekty s raznym intervalom mezhdu blokami TMS v otnoshenii kognitivnyh funkcij izucheny nedostatochno. Cel'yu raboty bylo ocenit' effekt dvuh teta-vspyshkami (iTBS) korotkim i dlinnym intervalami pokazateli rabochej pamyati (RP) u zdorovyh dobrovol'cev. V sluchajnom poryadke 16 uchastnikam provodili po odnoj sessii kazhdym protokolom (iTBS 0–15 — dva bloka iTBS levoj dorsolateral'noj prefrontal'noj kory (lDLPFK) 15 min nimi posleduyushchej stimulyaciej oblasti verteksa cherez 60 posle pervogo bloka; 0–60 blok lDLPFK, vtoroj lDLPFK pervogo, 0 odin dvumya kontrol'nyj protokol tri analogichnymi intervalami). RP ocenivali pomoshch'yu testa n-back pered pervym, vtorogo tret'ego blokov Statisticheski znachimyh effektov RP, a takzhe razlichij protokolami izmeneniyu pokazatelej ili kolichestvu uchastnikov, otvetivshih TMS, obnaruzheno ne bylo. Tendenciya statisticheskoj znachimosti pokazana dlya protokola 0–15). Krome togo, podtverzhdena nizkaya individual'naya vosproizvodimost' effekta iTBS. Perspektivnymi predstavlyayutsya issledovanie bolee krupnyh vyborkah dobrovol'cev, uchet drugih faktorov, potencial'no vliyayushchih (kolichestvo dlitel'nost' odnogo bloka).
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ژورنال
عنوان ژورنال: Vestnik RGMU
سال: 2023
ISSN: ['2070-7320', '2070-7339']
DOI: https://doi.org/10.24075/vrgmu.2023.011